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The “metan” command in Stata (version 13, StataCorp, USA) was used to conduct all of the meta-analyses.

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Important safety information from Pfizer, as posted on Chantix.

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Original anonymous reports were obtained from the four national pharmacovigilance centers that submitted these reports and assessed for reaction description and causality.

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Drug-drug interactions: proof of relevance (part I).

In the absence of this enzyme, diseased lung tissue in COPD is repaired more slowly.

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With the metabolic clearance of varenicline being so low, it is not unexpected that this would be challenging to study in vitro.

Patients treated with CHANTIX had a superior rate of CO-confirmed abstinence during weeks 9 through 12 (54%) compared to patients treated with placebo (19%) and from weeks 9 through 24 (35%) compared to subjects treated with placebo (13%).

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Although the data suggest preexisting mental illness has no impact on the likelihood of experiencing a psychiatric AE caused by varenicline, the small sample size within each of these publications prevents a definitive conclusion from being made regarding the safety of varenicline in patients with mental illness.

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Determination of the nicotine metabolite trans-3'-hydroxycotinine in urine of smokers using gas chromatography with nitrogen-selective detection or selected ion monitoring.

Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes.

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Bethesda, Md: National Institutes of Health, National Cancer Institute, NIH Publ No 97-4213, 1997.

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All services offered to you as part of this study, including the medication and the therapy, will be provided free of charge.

This report on medications is for your information only, and is not considered individual patient advice.

Evaluation of correlation of BODE index with health-related quality of life among patients with stable COPD attending a tertiary care hospital.

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