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What is the generic for Combigan? Combigan. Brimonidine/timolol (Combigan) is an expensive drug used in the eye to treat open-angle glaucoma and high pressure in the eyes. This drug is more popular than comparable drugs. There are currently no generic alternatives for Combigan.
Does eye pressure increase at night? Intraocular pressure rises during the night, hours after (or before) you see patients in your office. So, higher mean nocturnal IOP levels coupled with nocturnal drops in blood pressure can lead to low ocular perfusion and ischemic damage to the optic nerve.
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